Anna Bernardi Selected Research

DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)

4/2022	Glycomimetic ligands block the interaction of SARS-CoV-2 spike protein with C-type lectin co-receptors.
1/2018	Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition.
10/2016	Pseudo-Mannosylated DC-SIGN Ligands as Immunomodulants.
1/2016	Solution Behavior of Amphiphilic Glycodendrimers with a Rod-Like Core.
3/2015	Designing nanomolar antagonists of DC-SIGN-mediated HIV infection: ligand presentation using molecular rods.
4/2014	A multivalent inhibitor of the DC-SIGN dependent uptake of HIV-1 and Dengue virus.
4/2013	Selective targeting of dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) with mannose-based glycomimetics: synthesis and interaction studies of bis(benzylamide) derivatives of a pseudomannobioside.
2/2013	Structure of a glycomimetic ligand in the carbohydrate recognition domain of C-type lectin DC-SIGN. Structural requirements for selectivity and ligand design.
1/2012	A glycomimetic compound inhibits DC-SIGN-mediated HIV infection in cellular and cervical explant models.
8/2011	Second generation of fucose-based DC-SIGN ligands: affinity improvement and specificity versus Langerin.

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Anna Bernardi Research Topics

Disease

17	Infections 04/2022 - 07/2007
7	HIV Infections (HIV Infection) 10/2016 - 03/2010
4	Neoplasms (Cancer) 10/2020 - 01/2006
4	Virus Diseases (Viral Diseases) 01/2016 - 07/2011
3	Cholera 01/2017 - 02/2012
2	Human Influenza (Influenza) 01/2018 - 07/2016
1	Autoimmune Diseases (Autoimmune Disease) 10/2020
1	Hypersensitivity (Allergy) 10/2020
1	Schistosomiasis (Bilharziasis) 10/2020
1	Contusions 03/2017
1	Gliosis 03/2017
1	Traumatic Brain Injuries (Traumatic Brain Injury) 03/2017
1	Reperfusion Injury 03/2016
1	Ischemic Stroke 03/2016
1	Dengue (Dengue Fever) 04/2014
1	Brain Injuries (Brain Injury) 09/2012
1	Brain Ischemia (Cerebral Ischemia) 09/2012
1	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 05/2012
1	Pathologic Processes 01/2008
1	Guillain-Barre Syndrome 03/2007

Drug/Important Bio-Agent (IBA)

13	DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA 04/2022 - 07/2007
9	LigandsIBA 01/2018 - 01/2006
5	C-Type Lectins (C-Type Lectin)IBA 04/2022 - 07/2007
4	Proteins (Proteins, Gene)FDA Link 01/2016 - 01/2008
3	Pharmaceutical PreparationsIBA 07/2021 - 06/2014
3	LectinsIBA 01/2020 - 03/2010
3	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 03/2017 - 09/2012
3	CarbohydratesIBA 01/2016 - 07/2007
3	Antiviral Agents (Antivirals)IBA 04/2014 - 07/2007
2	Glycoproteins (Glycoprotein)IBA 04/2022 - 01/2021
2	Polysaccharides (Glycans)IBA 04/2022 - 10/2020
2	Blood Group Antigens (Blood Groups)IBA 08/2014 - 02/2012
2	Dendrimers (Dendrons)IBA 02/2013 - 07/2011
2	dendronIBA 01/2012 - 03/2010
1	MucinsIBA 10/2020
1	IonsIBA 01/2018
1	Ammonium CompoundsIBA 01/2018
1	EnzymesIBA 01/2018
1	Guanidine (Guanidine Nitrate)FDA Link 01/2018
1	salicylhydroxamic acid (SHAM)IBA 03/2017
1	Glial Fibrillary Acidic ProteinIBA 03/2017
1	glycodendrimer 13.3IBA 03/2017
1	Enterotoxins (Enterotoxin)IBA 01/2017
1	bicyclo(3.1.0)hexaneIBA 07/2016
1	Neuraminidase (Sialidase)IBA 07/2016
1	N-Acetylneuraminic Acid (Sialic Acid)IBA 07/2016
1	adenainIBA 08/2014
1	Cysteine Proteases (Cysteine Protease)IBA 08/2014
1	Peptide Hydrolases (Proteases)FDA Link 08/2014
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2014
1	Complement System Proteins (Complement)IBA 09/2012
1	CaspasesIBA 05/2012
1	ABO Blood-Group SystemIBA 02/2012
1	Cell Adhesion MoleculesIBA 01/2012
1	ChemokinesIBA 01/2012
1	PolyestersIBA 07/2011
1	Anti-Infective Agents (Microbicides)IBA 07/2010
1	IntegrinsIBA 03/2010
1	Intercellular Adhesion Molecule-3IBA 03/2010
1	OligosaccharidesIBA 01/2008
1	GlycoconjugatesIBA 01/2008
1	DisaccharidesIBA 07/2007
1	AntibodiesIBA 03/2007
1	GangliosidesIBA 03/2007
1	Integrin alphaVIBA 01/2006
1	Angiogenesis InhibitorsIBA 01/2006

Therapy/Procedure

3	Therapeutics 04/2017 - 07/2010